hrp0082p2-d3-396 | Fat Metabolism & Obesity (2) | ESPE2014

D2 Dopamine Receptor Agonists Influence in the Animal Model of Dietary Obesity

Viazava Liudmila , Solntsava Anzhalika , Sukalo Alexander , Dashkevich Elena , Stukach Yuliya

Background: Increased caloric intake in dietary obesity (DO) could be driven by central mechanisms regulating reward-seeking behavior. Leptin modulates the mesolimbic dopamine system and vice versa.Objective and hypotheses: We supposed D2 dopamine receptor agonists to influence weight gain and leptin level in genetically unmodified rats (GUR) with high caloric diet (HCD) as dietary obesity.Method: Male rats (n=48,...